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Pyridoxal phosphate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pyridoxal phosphate图片
CAS NO:54-47-7
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议
200 mg电议

产品名称
PLP
Vitamin B6 phosphate
Pyridoxal 5′-phosphate
PAL-P
Pyridoxyl phosphate
pyridoxal 5'-phosphate
磷酸吡哆醛
产品介绍
Pyridoxal phosphate 是维生素 B6 的活性形式,可抑制逆转录酶活性,用于研究迟发性运动障碍症。

产品描述

Pyridoxal Phosphate is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction.

体外活性

Pyridoxal phosphate results in an immediate reduction in the rate of DNA synthesis. Pyridoxal 5′-phosphate severely inhibits the DNA Polymerase and RNase H. Conjugation to pyridoxal phosphate fully inhibits NEIL2. Pyridoxal phosphate-conjugated NEIL2 shows much lower activity than the intact enzyme over a wide range of enzyme/substrate ratios. After Pyridoxal phosphate conjugation, the ability of NEIL2 to bind the THF-ligand is completely lost.

Cas No.

54-47-7

分子式

C8H10NO6P

分子量

247.14

别名

PLP;Vitamin B6 phosphate;Pyridoxal 5′-phosphate;PAL-P;Pyridoxyl phosphate;pyridoxal 5'-phosphate;磷酸吡哆醛

储存和溶解度

DMSO:40.5 mM
H2O:20.23mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years