OSIP-486823 is a microtubule-interfering agent with distinct biological effects on both protein kinase G (PKG) and microtubules.

OSIP486823 causes depolymerization of microtubules in interphase cells, inhibit spindle formation in mitotic cells, and induce multinucleated cells.?In vitro tubulin polymerization assays indicate that ?compound interact with tubulin directly to cause microtubule depolymerization and/or inhibit de novo tubulin polymerization.

200803-37-8

C29H28FNO4

473.54

CP248

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years