Estramustine 是一种与雌二醇相连的氮芥，通常为磷酸盐。它已被用于治疗前列腺肿瘤；还具有防辐射功能。它被前列腺细胞选择性吸收，并通过干扰微管动力学和降低血浆睾酮水平发挥抗肿瘤作用。

Estramustine is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties. Estramustine is selectively taken up by prostate cells and exerts antineoplastic effects by interfering with microtubule of dynamics and by reducing plasma levels of testosterone.

2998-57-4

C23H31Cl2NO3

440.4

LEO-275;NSC-89201;LEO275;NSC 89201;LEO 275;NSC89201;雌莫司汀

DMSO:55 mg/ml (124.89 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years