CK-666 是一种肌动蛋白相关蛋白 Arp2/3 复合物的细胞渗透性抑制剂。 它与 Arp2/3 复合物结合，稳定复合物的非活性状态，阻止 Arp2 和 Arp3 亚基进入活化的丝状短节距构象。

CK-666 is a cell-permeable inhibitor of actin-related protein Arp2/3 complex. It binds to the Arp2/3 complex, stabilizes the inactive state of the complex, blocking the movement of the Arp2 and Arp3 subunits into the activated filament-like (short pitch) conformation.

442633-00-3

C18H17FN2O

296.34

DMSO:125 mg/mL (421.81 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years