Maytansine 是从变叶美登木中分离的一种高效微管靶向天然产物,可诱导有丝分裂阻滞并在亚纳摩尔浓度杀死肿瘤细胞。
产品描述
Maytansine, an ansamycin antibiotic originally isolated from the Ethiopian shrub Maytenus serrata, inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site.
Cas No.
35846-53-8
分子式
C34H46ClN3O10
分子量
692.2
别名
Maitansine;美坦新;Maitansina;NSC153858;NSC-153858;NSC 153858
储存和溶解度
H2O:Insoluble
DMSO:60 mg/ml (86.68 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years