P11 acetate 是一种整合素 αvβ3-玻连蛋白相互作用拮抗剂 (IC50 = 2.74 nM)。

P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).

P11 acetate showed a strong antagonism against avb3-GRGDSP interaction(IC50 = 25.72 nM)[1]. P11 acetate inhibited the HUVEC proliferation due to the induction of HUVEC cell death through caspases activations and its mechanism is related with increased p53 expression[2].P11 acetate significantly inhibited bFGF-induced cell migration compared to the PBS control group[3].

TP1879L1

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years