A 286982 是一种有效的变构LFA-1/ICAM-1相互作用抑制剂，在 LFA-1/ICAM-1 结合和 LFA-1 介导的细胞粘附试验中，IC50分别为 44 和 35 nM。

A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1.

A 286982 is a selective inhibitor of LFA-1/ICAM-1 binding and LFA-1 with IC50 values of 44 nM and 35 nM, respectively[2].

280749-17-9

C24H27N3O4S

453.56

DMSO:45.35 mg/mL (100mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years