Phenazopyridine hydrochloride 是一种具有局部止痛作用的化学物质,常被用于缓解手术、损伤尿道及尿路感染引起的疼痛、刺激、不适和尿急。
产品描述
Phenazopyridine Hydrochloride is used orally as a urinary tract analgesic. Side effects of phenazopyridine hydrochloride administration can include nausea, interference with the oxygen-carrying capacity of red blood cells (methemoglobinemia), hemolytic anemia as well as renal and hepatic toxicity. It is reasonably anticipated to be a human carcinogen.
体外活性
Phenazopyridine可直接抑制正常大鼠膀胱的机械敏感性Aδ-纤维.
体内活性
Phenazopyridine可以增加细胞存活、强化神经细胞的分化、同步细胞分化状态以及减少非神经元和未分化细胞数量。
Cas No.
136-40-3
分子式
C11H12ClN5
分子量
249.7
别名
盐酸非那吡啶;Phenazopyridine HCl;Urodine;Pyridium
储存和溶解度
Ethanol:<1 mgml
DMSO:47 mg/mL (188.2 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years