Fosphenytoin sodium 是 phenytoin 的前体药物，具有抗惊厥等活性。它是电压门控钠通道阻滞剂。

Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker

Fosphenytoin has anticonvulsant activity in a mouse model of maximal electroshock seizures similar to that of phenytoin (ED50s = 16 and 8 mg/kg, respectively). It also has antiarrhythmic activity in isolated guinea pig atria and in anesthetized dogs. Formulations containing fosphenytoin have been used in the treatment of status epilepticus

92134-98-0

C16H13N2Na2O6P

406.241

磷苯妥英钠;Fosphenytoin sodium;ACC-9653

H2O:100 mg/mL (246.16 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years