Zabofloxacin hydrochloride is a potent and seletive bacterial type II and IV topoisomerases inhibitor, has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia.

In vitro, Zabofloxacin shows a highly potent activity against clinical isolates of penicillin-sensitive S. pneumoniae (minimum inhibitory concentration with MIC90 of 0.03 mg/L) and penicillin-resistant S. pneumoniae (MIC90: 0.03 mg/L). Against quinolone-resistant S. pneumoniae, zabofloxacin (MIC90: 1 mg/L) is more active than ciprofloxacin, sparfloxacin, and moxifloxacin.

623574-00-5

C19H21ClFN5O4

437.85

DW-224a

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years