KO-947是选择性ERK1/2激酶抑制剂，具有潜在的抗肿瘤作用。

KO-947 is a potent and specific inhibitor of ERK1/2 kinases.

KO-947 blocks ERK signaling and proliferation of tumor cells exhibiting dysregulation of MAPK pathway signaling, including mutations in KRAS, NRAS or BRAF, at low nanomolar concentrations.

1695533-89-1

C21H17N5O

355.39

DMSO:60 mg/mL (168.83 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years