CID-1067700 是泛GTPase抑制剂，可竞争性抑制大脑 7 (Rab7) 中的 Ras 相关蛋白，Ki为 13 nM。

CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases（Rab7 with a Ki of 13 nM).

CID-1067700 binds the nucleotide binding pocket of Rab7 with a Ki value of 13 nM, preventing BODIPY-linked GTP and GDP binding with EC50 values of 11.2 and 21 nM, respectively[1].

314042-01-8

C18H18N2O4S2

390.47

2-[[(苯甲酰基氨基)硫代甲酰]氨基]-4,7-二氢-5,5-二甲基-5H-噻吩并[2,3-C]吡喃-3-羧酸

DMSO:68 mg/mL(174mM),Need?ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years