ML098 是GTP结合蛋白Rab7的一种激活剂，EC50值为77.6nM。

ML-098 is an activator of the GTP-binding protein Rab7 (EC50: 77.6 nM).

ML098 (CID-7345532) functions by increasing the affinity of the GTPases for guanine nucleotides, leading to the hypothesis that these activators interact with GTPases bind to an allosteric binding site localized between switch regions I and II. ML-098 is an activator of the GTP-binding protein Rab7 with an EC50 of 77.6 nM which shows selectivity against the related GTPases cdc42, Ras, Rab-2A, and Rac1 (EC50s = 588.8, 346.7, 158.5, and 794.3 nM, respectively)[1].

878978-76-8

C19H19NO3

309.365

CID-7345532

DMSO:25 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years