TAK-981 是SUMOylation酶联反应的选择性抑制剂，具有潜在的免疫激活和抗肿瘤特性。

TAK-981 is a selective the SUMOylation enzymatic cascade inhibitor, has potential immune-activating and antineoplastic activities.

TAK-981 is able to increase the production of type 1 IFN, thereby increasing type 1 IFN-mediated signaling, TAK-981 activating innate effector cells and enhancing the antitumor innate immune responses[1].

TAK-981(A single sub-cutaneous injection) in naive Balb/c mice at the brachial lymph nodes induces activation of DCs[2].

1858276-04-6

C25H28ClN5O5S2

578.1

TAK-981

DMSO:75 mg/mL (129.74 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years