SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nM

SB-423557 elicits transient increases in plasma concentrations of PTH, resulting in increased bone mass and strength in both vertebrae and long bones compared to that of OVX controls.

351490-26-1

C28H36N2O4

464.6

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years