Ibutilide Fumarate 是一种 III 类抗心律失常药物,可作用于急性心梗阻塞。
产品描述
Ibutilide Fumarate is the fumarate salt form of ibutilide, a class III antiarrhythmic agent. Ibutilide exerts its effect by activating a slow, inward, predominately sodium current rather than by blocking outward potassium currents. This results in prolongation of atrial and ventricular action potential duration and refractory periods. Ibutilide slightly decreases the sinus rate and atrioventricular (AV) conduction and produces a dose-related prolongation of the QT interval.
Cas No.
122647-32-9
分子式
C44H76N4O10S2
分子量
885.23
别名
U70226E;Corvert Fumarate;富马酸伊布利特
储存和溶解度
H2O:44.3 mg/mL (100 mM)
DMSO:44.3 mg/mL (100 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years