Isovaleramide是抗惊厥剂，能够调节中枢神经系统的活性。

Isovaleramide is an anticonvulsant molecule isolated from Valeriana pavonii, which can inhibit the liver alcohol dehydrogenases.

研究Isovaleramide对小鼠,大鼠和兔的生殖毒性,其潜能远低于VPA.小鼠口服100 mg/Kg Isovaleramide,对最大电休克发作的保护指数达90％.

0.15% Isovaleramide在Rhodococcus sp. YH 3-3中诱导形成腈水合酶。300 μM Isovaleramide在体外实验中,抑制42% 3H-FNZ结合到位点。Isovaleramide浓度高达1000 μM时,不影响体外各种神经递质结合和吸收检测,说明其作用机制不涉及直接的受体介导作用。

541-46-8

C5H11NO

101.149

3-Methylbutanamide;异戊酰胺

H2O:<1 mgml
DMSO:16 mg/mL (158.2 mM)
Ethanol:16 mg/mL (158.2 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years