LEI110 是一种有效的 Phospholipase A2, group XVI (PLA2G16) 抑制剂，Ki 值为 20 nM。 LEI110 是 HRasLS 硫醇水解酶家族（即 PLA2G16、HRasLS2、RARRES3 和 iNAT）的选择性泛抑制剂。

LEI110 is a potent Phospholipase A2, group XVI (PLA2G16) inhibitor with an Ki value of 20 nM. LEI110 is a selective pan-inhibitor of the HRASLS family of thiol hydrolases (i.e., PLA2G16, HRASLS2, RARRES3 and iNAT).

LEI110 reduces cellular arachidonic acid levels in PLA2G16-overexpressing U2OS cells and oleic acid-induced steatosis in human HepG2 cells[1].

2313525-90-3

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years