HMG499是有效，选择性的HMG-CoA还原酶抑制剂，EC50为 0.41 μM。HMG499可消除他汀类药物诱导的HMGCR积聚，并且降低血清胆固醇水平，减少动脉粥样硬化。

HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC 50 of 0.41 μM. HMG499 can eliminate statins-induced accumulation of HMGCR, lower serum cholesterol levels and decrease atherosclerosis [1].

2416941-68-7

C33H54O3

498.78

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years