TyROSine 是一种非必需氨基酸，对后部皮层中柠檬酸合成酶具有抑制活性。

L-tyrosine is a naturally occurring tyrosine and is synthesized in vivo from L-phenylalanine, considered a non-essential amino acid. L-Tyrosine is the levorotatory isomer of the aromatic amino acid tyrosine.

L-tyrosine in vitro inhibits citrate synthase activity in the posterior cortex. Succinate dehydrogenase activity is increased in the posterior cortex, hippocampus, striatum and liver. Complex I activity is inhibited in the hippocampus, complex II activity is also inhibited in the hippocampus and in the posterior cortex and liver, complex II–III activity is not altered by L-tyrosine and complex IV activity decreased in the posterior cortex[1].

Acute administration of L-tyrosine inhibits malate dehydrogenase and complex II, II–III and IV of the mitochondrial respiratory chain activity in the posterior cortex and liver of rats. The succinate dehydrogenase enzyme and complex I activity are inhibited in the posterior cortex and increased in the striatum[1].

60-18-4

C9H11NO3

181.19

Tyrosine;P-Tyrosine;L-p-Tyrosine;L-酪氨酸;酪氨酸;(S)-Tyrosine

DMSO:Insoluble
H2O:Insoluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years