Mirodenafil dihydrochloride 是一种磷酸二酯酶5(PDE-5)抑制剂,可作用于勃起功能紊乱的研究。
产品描述
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
体内活性
Mirodenafil, in doses of 50 or 100 mg, significantly improved erectile function and was well tolerated in a representative population of Korean men with broad-spectrum ED of various etiologies and severities [1]. The concurrent administration of mirodenafil with alcohol was not associated with clinically significant hemodynamic changes in these healthy male volunteers in Korea. The pharmacokinetics of mirodenafil were not significantly altered by this concurrent administration. Mirodenafil administered with alcohol had a tolerability profile comparable to that of mirodenafil alone [2].
Cas No.
862189-96-6
分子式
C26H39Cl2N5O5S
分子量
604.59
别名
SK-3530 dihydrochloride;米罗那非二盐酸盐
储存和溶解度
DMSO:100 mg/mL (165.40 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years