Mirodenafil 是一种磷酸二酯酶5(PDE-5)抑制剂,可用于勃起功能紊乱的研究。
产品描述
Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
体外活性
The pharmacoki-netics of mirodenafil were not significantly altered by this concurrent administration. Mirodenafil (50 or 100 mg), obviously improved erectile function and was well tolerated in a representative population of Korean men with broad-spectrum ED of various etiologies and severities [1]. Mirodenafil administered with alcohol had a tolerability profile comparable to that of mirodenafil alone [2]. The concurrent administration of mirodenafil with alcohol was not associated with clinically significant hemodynamic changes in these healthy male volunteers in Korea. The coadministration of ketoconazole and rifampicin resulted in significant changes in systemic exposure to mirodenafil, in these healthy Korean male volunteers [3].
Cas No.
862189-95-5
分子式
C26H37N5O5S
分子量
531.67
别名
米罗那非;SK3530
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years