SHIP2-IN-1 是一种 SHIP2 抑制剂，IC50=2 μM。它能够使 GSK3β 的 Ser9 位点磷酸化，抑制 GSK3β 的活化。它可用于研究阿尔滋海默症。

SHIP2-IN-1 is a potent SHIP2 inhibitor(IC50 : 2 μM),and used in the research of Alzheimer’s disease.

PI(3,4)P2 production in HT22 cellssignificantly inhibited by SHIP2-IN-1 (10 μM) .

2252247-80-4

C17H13Cl2FN4O

379.22

DMSO:90 mg/mL (237.33mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years