Sodium etidronate 是一种内源性pyrophosphate的合成治疗性diphosphonate类似物。作为称为bisphosphonates盐类药物家族的一员，etidronate disodium与内源性pyrophosphate的不同之处在于其对酶水解的耐受性。该药剂吸附hydroxYAPatite细胞并减少破骨细胞的数量，从而抑制异常骨吸收。 Etidronate 还可以直接刺激成骨细胞的骨形成。

Etidronate Disodium is a synthetic therapeutic diphosphonate analog of endogenous pyrophosphate. As a member of the family of drugs known as bisphosphonates, etidronate disodium differs from endogenous pyrophosphate in its resistance to enzymatic hydrolysis. This agent adsorbs to hydroxyapatite cells and reduces the number of osteoclasts, thereby inhibiting abnormal bone resorption. Etidronate may also directly stimulate bone formation by osteoblasts.

7414-83-7

C2H6Na2O7P2

249.99

依替膦酸钠;Didronel

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years