S-methyl-KE-298 是 KE-298 的活性代谢物。KE-298 抑制类风湿关节炎滑膜细胞产生基质金属蛋白酶。

S-methyl-KE-298 is the second main metabolite in plasma,is a methyl conjugate of deacetyl-KE-298.KE-298 inhibits matrix metalloproteinase (MMP-1) production from rheumatoid arthritis (RA) synovial cells.

In vitro protein binding of S-methyl-KE-298 is high in rat (>97%), dog (>89%) and human plasma (>99%), respectively[2].

143584-75-2

C13H16O3S

252.33

DMSO:100 mg/mL (396.31 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years