17α-Estradiol 是一种雌性激素，可抑制5α-Reductase，在雄原性脱发的研究中有潜力。

Endogenous estrogen receptor ligand (Ki values are 0.2 and 1.2 nM for ERα and ERβ receptors respectively).

Na+-Ca2+ exchange activity is determined by assaying Na+-dependent 45Ca2+ uptake as reported previously. Briefly, the cells are preincubated in Hanks' balanced saline solution (HBSS) for 20 min, and the medium is switched to HBSS containing 45Ca2+?and incubated for 5 min. To increase intracellular Na+?concentration, 1 mM ouabain plus 20 μM monensin (for astrocytes and microglia) and 10 μM monensin (for neurons) are used. Monensin is added simultaneously with the isotope. Ouabain is added 5 min before monensin in astrocytes and microglia. SEA0400 and KB-R7943 are added 5 min before monensin and present during 45Ca2+?uptake reaction.

57-91-0

C18H24O2

272.388

雌二醇;17α-Estradiol;Alfatradiol;α-雌二醇;Epiestradiol;Epiestrol

DMSO:100 mM
Ethanol:100 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years