D-erythro-Sphingosine 是一种非常有效的p32激酶活化剂,EC50为 8 μM。它也是一种PP2A激活剂,抑制蛋白激酶 C (PKC)。
产品描述
D-erythro-Sphingosine is a protein kinase C (PKC) inhibitor. D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator
体外活性
D-erythro-Sphingosine inhibits protein kinase C in vitro[1]. D-erythro-Sphingosine has been shown to inhibit protein kinase C, which affects cell regulation and several signal transduction pathways, and exhibits antitumor promoter activities in various mammalian cells[2].
Cas No.
123-78-4
分子式
C18H37NO2
分子量
299.499
别名
鞘氨醇;trans-4-Sphingenine;D-鞘氨醇;erythro-C18-Sphingosine;Erythrosphingosine
储存和溶解度
DMSO:250 mg/mL (834.75 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years