O-304 是 AMP 活化蛋白激酶 (AMPK) 的泛激活剂，可通过抑制 pAMPK 的去磷酸化来增加 AMPK 活性，可用于 2 型糖尿病和相关心血管并发症的研究。

O-304 is a pan-activator of AMP-activated protein kinase (AMPK).

In vivo, O-304 (100 mg/kg) prevents high-fat diet-induced increases in fasted glucose and plasma insulin levels and development of insulin resistance, as well as increases calf muscle pAMPK levels in mice.

1261289-04-6

C16H11Cl2N3O2S

380.24

DMSO:30 mg/mL (78.90 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years