产品描述
TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).
体外活性
TP-472 has a high potency for BRD9 with Kd of 33 nM and BRD7 with Kd of 0.34 μM, with >30-fold selectivity over other Brds[1]. TP-472 (1 μM, 3 μM; 24-216 hours) yields concentration-dependent growth defects in ESCs[2].
Cas No.
2079895-62-6
分子式
C20H19N3O2
分子量
333.38
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years