NEO2734 是一种具有口服活性的选择性 p300/CBP 和 BET 溴结构域抑制剂，其IC50值均小于30 nM，可用于前列腺癌的研究。

NEO2734 is an orally active and selective inhibitor of p300/CBP and BET bromodomain(IC50 of<30 nM for both p300/CBP and BET bromodomains).

NEO2734, a novel dual inhibitor of BET and CBP/p300, is active in both hotspot mutant (F133V) and non-hotspot mutant (Q165P) PCa cells in vitro and in vivo[1].

2081072-29-7

C22H24F3N3O3

435.447

EP31670

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years