GSK 5959 是一种选择性的、细胞渗透性的BRPF1溴端结构域的抑制剂，其IC50值为 80 nM。她对 BRPF1 的选择性是 35 个其他溴结构域的 100 倍以上。

GSK-5959 is an effective, specific and cell permeable BRPF1 bromodomain inhibitor (IC50: ~80 nM). The selectivity of GSK-5959 for BRPF1 is >100-fold over a panel of 35 other bromodomains, including BRPF2/3 and BET family bromodomains.

901245-65-6

C22H26N4O3

394.475

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years