TGFBR1-IN-1 is an inhibitor of ALK5 (IC50 of 10-100 nM).

TGFβRI-IN-2 (compound 18) at 1 μM shows a 31% inhibition of MAP3K2 (MEKK2) with an IC50 value of 2.2?μM.

2170830-26-7

C23H17N5O2S

427.48

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years