BiNODeNOSon 是一种选择性A2A腺苷受体激动剂，KD为270 nM。它是一种短效冠状动脉血管扩张剂，作为放射性示踪剂的辅助剂，用于心肌应激成像。

Binodenoson is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stress imaging[1].

2-(cyclohexylmethylidenehydrazino)adenos (30-300 nM) decreases oxidative activity of tumor necrosis factor-α–primed FMLP-stimulated polymorphonuclear leukocytes in human whole blood and acts synergistically with Rolipram[1].

2-(cyclohexylmethylidenehydrazino)adenos (infused 0-0.9 μg/kg/h; adult Wistar rat; rat bacterial meningitis model), with or without rolipram (0-0.01 μg/kg/h), inhibits pleocytosis and reduces the lipopolysaccharide-induced increase in blood-brain barrier permeability (BBBP), indicative of decreased neutrophil-induced damage[1].

144348-08-3

C17H25N7O4

391.432

比诺地松;2-(cyclohexylmethylidenehydrazino)adenos;MRE-0470;WRC 0470

DMSO:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years