AdeNOSine A1 receptor activator T62 是腺苷 A1 受体的变构增强剂，有镇痛作用。

Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve-injury pain[1][2][3].

Adenosine A1 receptor activator T62 (0.3-3 μg; intrathecal administration; male SpragueDawley rats) treatment produces a dose-dependent antihypersensitivity effect. However it has no effect on ambulation or activity level[1].

Intrathecal T62 of Male SpragueDawley rats (250 g) after paw incision surgery with the dose of 0.3 μg, 0.5 μg, 1 μg, and 3 μg, produced a dose-dependent antihypersensitivity effect, with no effect on ambulation or activity level. The ED40 (95% confidence interval) for T62 was 0.77 (0.63-0.91) microg.

40312-34-3

C15H14ClNOS

291.8

DMSO:75 mg/ml (257.03 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years