您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Naloxone benzoylhydrazone
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Naloxone benzoylhydrazone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Naloxone benzoylhydrazone图片
CAS NO:119630-94-3
包装:10 mg
市场价:7617元

产品名称
NalBzoH
产品介绍

产品描述

Naloxone benzoylhydrazone is a prototypic κ3-opioid receptor agonist, and a partial agonist at the cloned μ and δ opioid receptors, and an antagonist at opioid-like NOP receptors, has potently analgesia effect.

体外活性

At the κ-opioid receptor (KOR), Naloxone benzoylhydrazone stimulates [35S]GTPγS binding with pEC50 of 9.70 and inhibits cyclic AMP formation (pEC50=9.45). In CHO cells expressing the δ-opioid receptor (DOR), Naloxone benzoylhydrazone increases [35S]GTPγS binding (pEC50=8.49) and inhibits cyclic AMP formation (pE50=8.61)[1].

Cas No.

119630-94-3

分子式

C26H27N3O4

分子量

445.51

别名

NalBzoH

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years