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Tyr-Gly-Gly-Phe-Met-OH
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tyr-Gly-Gly-Phe-Met-OH图片
CAS NO:58569-55-4
包装与价格:
包装价格(元)
10 mg电议
25 mg电议
50 mg电议
100 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
蛋氨酸脑啡肽
Met-Enkephalin
[MET5]脑啡肽
Methionine enkephalin
产品介绍
Tyr-Gly-Gly-Phe-Met-OH 是天然存在的内源性阿片肽、metenkephalin 和 zeta-和 delta-阿片受体激动剂的合成形式,是 mu-阿片受体激动剂,具有潜在的镇痛、神经调节、免疫调节、抗炎、抗肿瘤作用以及镇痛、抗抑郁和胃肠运动调节活性。

产品描述

Tyr-Gly-Gly-Phe-Met-OH, is a naturally occurring, endogenous opioid peptide that inhibits tumor growth via binding to the opioid receptor.

体外活性

Tyr-Gly-Gly-Phe-Met-OH,as know as Methionine enkephalin (MENK), an endogenous neuropeptide has a crucial role in both neuroendocrine and immune systems.?MENK is believed to have an immunoregulatory activity to have cancer biotherapy activity by binding to the opioid receptors on immune and cancer cells.?Clinical trial studies in cancer patients have shown that MENK activates immune cells directly and by inhibiting regulatory T-cells (Tregs).?MENK may also change the tumor microenvironment by binding to opioid receptor on or in cancer cells.?All of these mechanisms of action have biologic significance and potential for use in cancer immunotherapy.?Furthermore, they reveal a relationship between the endocrine and immune systems.

Cas No.

58569-55-4

分子式

C27H35N5O7S

分子量

573.67

别名

蛋氨酸脑啡肽;Met-Enkephalin;[MET5]脑啡肽;Methionine enkephalin

储存和溶解度

DMSO:40 mg/mL (69.73 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years