Galnon 是一种甘丙肽受体激动剂,可改善内在的皮质骨组织特性。
产品描述
Galnon is a galanin receptor agonist, improves intrinsic cortical bone tissue properties
体内活性
Galnon has been characterized to inhibit seizures, decrease feeding behaviour, diminish physical signs of opiate withdrawal and to alleviate heat-hyperalgesic response to partial sciatic nerve injury[1]. Galnon, a GAL receptor agonist, may enhance osteoclastic bone resorption in OVX rats. Although galnon reduced bone volume, biomechanical testing revealed that bone of galnon-treated animals was mechanically superior per unit area. Taken together, galnon simultaneously improves the intrinsic quality of cortical bone whilst stimulating osteoclastic activity in the OVX rat model[2].
Cas No.
475115-35-6
分子式
C40H46N4O6
分子量
678.83
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years