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RWJ-51204
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
RWJ-51204图片
CAS NO:205701-85-5
包装:5 mg
市场价:7000元

产品介绍

产品描述

RWJ-51204 is a partial agonist of GABA(A) receptor (Ki: 0.2-2 nM).

体外活性

RWJ-51204 binds to receptors with Ki ranging from 0.2 to 0.6 nM in the cerebral cortex, cerebellum, or medulla-spinal cord.

体内活性

RWJ-51204 is effective in the conflict test in monkeys (ED50 of approximately 0.5 mg/kg p.o.). RWJ-51204 is orally active in anxiolytic efficacy tests. RWJ-51204 effectively impairs rotarod performance in rats (ED50 = 0.12 mg/kg), and all rats given RWJ-51204 orally at 30 mg/kg exhibit sedation, reduced skeletal muscle tone, and impairment of rotarod performance.

Cas No.

205701-85-5

分子式

C21H19F2N3O3

分子量

399.39

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years