Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).

Foliglurax is a highly selective and potent mGlu4 receptor PAM. It has a marked brain-penetrance feature, which might revolutionize the field of mGlu4 receptor drug targeting in CNS disorders [2].

1883329-51-8

C23H23N3O3S

421.51

PXT002331

DMSO:5.2 mg/mL (12.34 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years