NPS2390 是钙敏感受体抑制剂，也是 mGluR1 和 mGluR5 的非竞争性拮抗剂。

NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)

Treatment of NPS2390 was conducive to inhibit the proliferation and reverse phenotypic modulation of PASMCs by regulating autophagy levels.

226878-01-9

C19H21N3O

307.397

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years