VU0360172 是 mGlu5 受体的正变构调节剂（EC50 = 16 nM；Ki = 195 nM）。

VU0360172 is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM).

VU0360172 stimulates polyphosphoinositide (PI) hydrolysis in vivo, which is abrogated in mGlu5 receptors gene deleted mice[4].

1310012-12-4

C18H15FN2O

294.32

VU 0360172;VU-0360172

DMSO:83 mg/mL (282.01 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years