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Bromocriptine mesylate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bromocriptine mesylate图片
CAS NO:22260-51-1
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
CB-154
甲磺酸溴隐亭
产品介绍
Bromocriptine mesylate 是一种有效的多巴胺受体激动剂,以最高的亲和力结合 D2 受体,Ki 为 2.5 nM。

产品描述

Bromocriptine is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)

体外活性

The ergot alkaloid bromocriptine (BKT) was found to act as a strong inhibitor of purified neuronal nitric oxide synthase (NOS) (IC50 = 10 +/- 2 microM) whereas it was poorly active towards inducible macrophage NOS (IC50 >100 microM). BKT affects the activation of NOS by calmodulin, as it not only inhibits L-arginine oxidation to NO and L-citrulline but also NADPH oxidation and calmodulin-dependent cytochrome c reduction catalyzed by neuronal NOS. These results suggest that BKT could exert some of its therapeutic effects by interfering with the NOS-dependent formation of nitric oxide and/or superoxide ion in various tissues.

Cas No.

22260-51-1

分子式

C33H44BrN5O8S

分子量

750.71

别名

CB-154;甲磺酸溴隐亭

储存和溶解度

DMSO:30 mg/mL (39.96 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years