产品描述
D2343 is an agonist of β2-adrenoceptor. It also is an inhibitor of α1- adrenoceptor.
体外活性
D2343 shows in addition an alpha 1-receptor inhibitory activity [1]. The beta 2-agonistic and alpha 1-antagonistic drug D2343 inhibits the evoked contractions in a concentration related fashion with 50% effect at 9.6 μM [2].
体内活性
D2343 has shown an ability to relax the uterine muscles to the same degree as Terbutaline or even more, especially when the two drugs are compared in preparations from rabbit and rat. D2343 has been compared to the beta 2-agonist Terbutaline on oestrogenized uterine preparations from rat and in myometrial strips from homo and rabbit [1].
Cas No.
72734-63-5
分子式
C20H27NO3
分子量
329.43
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years