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Eledoisin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Eledoisin图片
CAS NO:69-25-0
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议

产品名称
依来多辛
Eledone peptide
产品介绍
Eledoisin 是一种特异性的NK2和NK3受体的激动剂。

产品描述

Eledoisin is a specific agonist of NK2 and NK3 receptors.Eledoisin is an undecapeptide of mollusk origin, belonging to the tachykinin family of neuropeptides.

体外活性

Eledoisin increases the value recorded under basal conditions by 24.5±3.7%; while this stimulation is significantly (P<0.01) lowered to 13.1±1.9% by the simultaneous presence of CP99994. The same protocol is also used to characterize the sensitivity of Eledoisin stimulation to 0.1 μM SR48968 or 0.1 μM SB222200. SR48968 significantly (P< 0.01) lower the stimulation by Eledoisin, while SB222200 has no effect. Eledoisin stimulation is reduced by CP99994 and SR48968, NK1 and NK2 antagonists, respectively[1].

体内活性

Injection of Eledoisin (0.1-1 nmol/kg) into rats produces a biphasic cardiovascular response that consists of an initial fall of systemic blood pressure (8-15 mm Hg) followed by a rise (20-22 mm Hg).

Cas No.

69-25-0

分子式

C54H85N13O15S

分子量

1188.4

别名

依来多辛;Eledone peptide

储存和溶解度

H2O:18.15 mg/mL (15.27 mM),Need ultrasonic and warming
Powder: -20°C for 3 years
In solvent: -80°C for 2 years