Neurokinin A(4-10) TFA(97559-35-8 free base) 是一种速激肽 NK2 受体激动剂。

Neurokinin A (4-10) TFA is a tachykinin NK2 receptor agonist[1].

Neurokinin A (NKA) and its truncated form NKA(4-10) are potent spasmogens of human colon circular muscle, an action mediated exclusively via tachykinin NK2 receptors. A structure-activity study of the neurokinin A (NKA) fragment NKA(4-10) is performed to investigate the importance of amino acid residues for receptor efficacy, potency and affinity at the NK2 receptor in human colon circular muscle. A high density of NK2 receptors has been demonstrated in this tissue, using in vitro autoradiography and radioligand binding[1].

TP1385

C36H55F3N8O12S

880.93

Neurokinin A(4-10) TFA

H2O:< 0.1 mg/mL (insoluble)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years