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Tradipitant
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tradipitant图片
CAS NO:622370-35-8
包装与价格:
包装价格(元)
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议
100 mg电议
200 mg电议
1 mL*10 mM(in DMSO)电议

产品名称
VLY-686
LY686017
产品介绍
Tradipitant 是一种有效的神经激肽-1 拮抗剂。

产品描述

Tradipitant is an antagonist of neurokinin-1.

体外活性

Tradipitant binds to sections of guinea pig brain with a distribution similar to that previously reported for NK-1 receptors. Areas with the highest density are the accessory olfactory nucleus, anteroventral thalamic nucleus, paraventricular hypothalamic nucleus central amygdaloid nucleus (lateral), and the medial amygdaloid nucleus [1].

体内活性

Tradipitant (intravenously administered) treatment localizes in the guinea pig brain and has a distribution similar to that described for the NK-1 receptor using agonist or antagonist radioligands [1].

Cas No.

622370-35-8

分子式

C28H16ClF6N5O

分子量

587.9

别名

VLY-686;LY686017

储存和溶解度

DMSO:60 mg/ml (102.06 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years