Pizotifen 是5-HT2受体的有效拮抗剂，并对5-HT1C有高亲和力。它是一种强血清素和色胺拮抗剂，具有较弱的抗胆碱能、抗组胺和抗激肽作用，还具有镇静和刺激食欲的特性。

Pizotifen is a strong serotonin and tryptamine antagonist, with weak anticholinergic, anti-histaminic and anti-kinin effects. It also possesses sedative and appetite-stimulating properties. Pizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraine. Sandomigran is available in number of countries excluding the United States.

15574-96-6

C19H21NS

295.44

Pizotyline;BC-105;苯噻啶

DMSO:20 mg/mL (67.70 mM),Need ultrasonic
H2O:< 0.1 mg/mL (insoluble)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years