CNQX disodium 是一种有效的、竞争性的 AMPA /海藻酸酯受体 (AMPA/kainate receptor) 拮抗剂，IC50分别为 0.3 μM 和 1.5 μM。它能够阻止大鼠恐惧增强的表达，是一种竞争性的非NMDA受体拮抗剂。
产品描述
CNQX disodium is a competitive non-NMDA receptor antagonist and competitive AMPA/kainate receptor antagonist in neuronal cultures.
体内活性
The ED50 for ?CNQX was 45.9+/-4.65 microg, respectively.?Intrathecal injection of a combination of CNQX and gabapentin produced a strong synergistic antiallodynic effect in neuropathic rats[1].
Cas No.
479347-85-8
分子式
C9H2N4Na2O4
分子量
276.119
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
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