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NKH477
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NKH477图片
CAS NO:138605-00-2
包装:100 mg
市场价:8726元

产品名称
Colforsin dapropate hydrochloride
产品介绍

产品描述

NKH477 is a novel water-soluble forskolin derivative that improves cardiac failure mainly through its beneficial effects on diastolic cardiac function. NKH477 shows an antiproliferative effect in vivo with an altered cytokine profile to inhibit the acute rejection of rat orthotopic lung allografts. NKH477 directly activates the catalytic unit of adenylate cyclase and enhances intracellular cAMP .

体内活性

NKH477 (p.o.; 1-3 mg/kg/day; days 3 and 5) prolonged lung allograft survival in a dose dependent manner.

Cas No.

138605-00-2

分子式

C27H44ClNO8

分子量

546.09

别名

Colforsin dapropate hydrochloride

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years