Co 101244 hydrochloride 是一种含有 NR2B 的 NMDA 受体拮抗剂。

Co 101244 hydrochloride is an NR2B-containing NMDA receptor antagonist.

Co 101244 enhances neuroprotection and reduces NMDA-evoked Ca2+?elevations effectively [1].

Administration of 1 mg/kg s.c. Co 101244 displayed antidyskinetic effects with the reduction of 67% while sparing levodopa motor benefit[1].

193356-17-1

C21H28ClNO3

377.91

4-Piperidinol, 1-[2-(4-hydroxyphenoxy)ethyl]-4-[(4-Methylphenyl)Methyl]-,hydrochloride;Co 101244盐酸盐

H2O:<35mg>DMSO:<17.5mg/ml(46.31mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years